Plastic Molding Company: Everything About Molding Process
All plastic materials demand a molding process, whether a small or a large Plastic Molding Company needs to ensure high-quality molding. In addition, there is the ever-increasing use of plastics from automobiles to synthetic human body parts.
The molding process involves shaping raw liquid plastic, pellets, sheets, or powder into different simple and complex shapes using rigid frames known as mold or matrix.
Moreover, the pellets are loaded into the hopper, a part of the mold where they are heated until they are in a soft, molten, or semi-liquid state.
You May Also Read: Plastic Injection Molding Factory: Modern Vs Conventional Molding
Moreover, within the heating cylinder, a screw mixes the molten material and pushes it to the cylinder's end. The screw controls the speed and pressure of molted material.
Also, the material is allowed then to cool down and set; then the mold is opened or removed the plastic products are ejected automatically out of the machine. Also, the control of thermal processes is vital in the production of high-value plastic products.
Plastic Molding Company: Techniques of Molding Processes
There are several methods used to prepare plastic. Below is an overview of the process!
Injection Molding process
It is used to make custom, intricate, plastic parts in various large scale production by injecting plastic material under high pressure into the mold. In addition, the thermostat heats the product faster, cheaper, and form a better product. The mold is allowed to cool, and a plastic part is released when the mold is opened.
Moreover, the sizeable sized machine produces significant parts like dashboards or bumpers, and small machines produce specific parts such as switches, surgical devices, or plastic bottle caps. Products have good dimensional accuracy.
There are many types of injection molding.
The Rubber Injection Molding.
The rubber is directly vulcanized from the barrel to mold. It happens in intermittent operations, but the molding cycle is short.
Plastic Injection Molding
Molten plastics are used in molds obtained by the cooling process. A particular injection molding machine is used to make plastics.
Mold Injection Molding
In this case, two silicone rubber materials combine into a mixture and produce final parts in one day, such as seals, connectors, cables, medical devices, kitchen devices, and infant products.
The final shape of the product requires no other finishing processes. It is possible to create many details using the Injection molding process.
Plastic sheets and temperature is used in a mold. There is a variety of thermoforming plastics in colors, thickness, and finishes.
Also, different types of molds are used to create3D products: disposable cups, plates, lids, trays, fridge liner, and auto parts. Tooling cost is low, medium production rate. Thermoplastics can be recycled again and again.
In this method, two materials combine to form one object or one part.
There are two types of material used in over-molding. One part is known as a substrate, and the other is over-molding material. Substrate materials are plastic, metal, glass, etc.
Over molding material include rubber and thermoplastics. It eliminates complicated processes and reduces the manufacturing cost, and gives the product a firm grip, specific features.
A liquid is poured into a specifically designed mold cavity allowed to cool and solidify. The hardened part is known as casting. Thus mold is removed from the casting. Heavy machines and beds, and ships are cast into the required size. Dip molding coating process
It is another plastic manufacturing process where a heated metallic structure in a PVC tank is called plastisol. The plastic is separated from the mold part upon cooling medical.
In addition, Plastic covering makes a protective layer as a finishing and smart look. The plastic coating is done around the mold by the cooling process.
Rotational Molding/Rotomodling Process
The rotational molding process was used in 1950 to make the dolls' heads, and in 1960, s rotational molding allows to make large and hollow parts. So, in-mold liquid or powder resin is kept and rotated in an oven, so even wall plastic is created. There is no wastage of material during this process.
Moreover, this method number of products are made like large hollow simple shape containers, car parts, recycling bin, and slides. Tool costs are less as compared to the other methods of molding like injection and blow molds.
Blow molding process
In this method, machines heat the plastic and inject air like a balloon to make delicate hollow parts of various sizes that shape the mold's walls. Then it is cooled, and when it is hardened, it is ejected from the mold. Bottles, cans, drums, and tanks are produced by using blow molding processes.
Furthermore, it is cheaper, faster, and economical than the injection molding method but more costly than rotational molding. It has a low production rate.
Plastic Molding Company offers Compression Molding
Heated mold melts the plastic or metals to press to make a specific, unique shape and durability. Also, it is cost-effective and efficient. Cooling and removing the extra parts is done as the final steps.
Final parts are strong and durable and are used in different applications. It is used in automotive parts, fiberglass thermosetting resin, household appliances, hood spoilers, and smaller auto parts.
It is a unique process; a die is used in this method, not a mold. A long, uniform, hollow, solid tubular shape with complex with constant cross-section shape is produced as an end product.
So, when the extrusion cools, it is removed from the machine. PVC piping, tubes, straw, dependable rods, wire, cables, strips window frames, hoses, plastic gutters, and straws are included.
Thus, the cost of extrusion molding is low, but the production rate is high because of the simplicity of die and machine.
The machine trims around the domes or neck of bottles made by blow molding at a higher and efficient speed. There is no leakage from the bottles.
Plastic sheets are heated on to a single surface. Original silicone made a mold by a vacuum. This process takes a few days to become a functional prototype. In addition, Plastic sheets are prepared with high-quality fine details. This process is costly for a number of parts.
Preheated material is used in the mold cavity. Moreover, the mold is closed with a plug and then compressed the material. It is used to make flat or curved parts. There is little waste, and it cost low.
You May Also Read: Why Automation of Plastic Molding is Important?
Take Away on Plastic Molding Company
In short, the engineers help you to understand the type of design and product suitable for your needs through the best manufacturing process.
If you are looking for more information, contact us today. We, SZ-Changhong, are the leading molding company. Therefore, we promise premium quality injection molding, molding designing, and several other services.
Modern Plastic Injection Molding Factory: An emblem of High quality and Precision with Faster and Economic production.
Starting from Lego toys to the high-tech Tesla industry, Plastic Injection Molding Factory is revolutionizing the world around us in a faster and easier way.
Plastic Injection Molding Factory is a method of molding by injecting molten plastic into different molds to shape plastic parts for daily use items. The method is now widely acknowledged as the most revolutionized method of processing and producing plastic products and parts in bulk.
You May Also Read: Why Automation of Plastic Molding is Important?
Origin of existence
The process of molding plastic originated back in the 19th century. The method was invented in the year 1872 when two manufacturers Isaiah and John Hyatt invented the molding machine to mold plastic.
The molded plastic to manufacture daily used items like combs, buttons, etc. Thus, this first leap proved to a breaking point in the plastic manufacturing industry.
How Contemporary Plastic Injection Molding Factory revolutionizing the modern world?
As in today, we cannot think of the world we are in without the invention and utility of modern computers and technology. Similarly, these technological devices would not even exist without the presence of such an advanced, high quality, reliable, and flexible modern plastic molding industry.
Modern plastic injection molding factory paved ways for modern technological devices to step into the real world.
Utility and Advantages
Modern Plastic industry using an injection model is coming up in each passing day with economic, reliable, complex, and quality plastic models and solutions.
These solutions are in daily use for multiple ranges of applications. The molded plastic parts are widely used in every industry because of its durable and reliable nature in terms of corrosion and erosion.
Accuracy in Complex Injection Molding:
The modern plastic injection molding factory uses a variety of methods and modern techniques of injecting plastic into complex and highly detailed molds.
It creates a complex plastics design with several details and features. The basic working model of the injection molds uses high pressure as its main subject. This, thus, exposes plastic to hard press, which helps in getting the complex and desires shapes/designs in real-time.
As opposed to the conventional molding method, the modern molding industry makes it easier for the plastic to get in shape by creating intricate designs and shapes.
This method in plastic products comes up with such precision that it is impossible to think of in using the conventional methods of plastic molding.
The level of precision in the plastic injection molding factory is extremely accurate. A single manufacturing unit can easily fabricate a plastic model of any type to a level of 0.001 inches.
This process is known as precision molding. The process is completely automated. Therefore, it remains inexpensive for the manufacturers even if they are to develop the most complex designs. Yet, this is the most sophisticated method of molding complex and reliable designs in the market.
The process of precision molding differs largely from the conventional molding machines. This is because conventional molding machines lack such detailed precision, quality, and durability in design. Whilst, precision molding includes complex geometric in manufacturing the complex, precise plastic molds.
High-Quality in Injection Molding:
The nature and use of plastic have changed over time. The plastic injection molding factory has revolutionized the plastic products that contain high quality, durability, and precision as the basic elements in all items.
The conventional methods of manufacturing produce hard and heavy plastic products. Whereas, the modern molding techniques and technology using injection have enabled the industry to design lightweight products. But these are stringent materials that last even in the most rugged weather having extremely hot /cold conditions.
The modern injection methods are making it possible for the manufacturers to add the fillers in injection molds. These fillers are missing in the conventional methods of plastic molding. These fillers like calcium, silica, clay, etc., thus add quality and variety of strength to plastic depending upon the usage.
The strength and stiffness of the plastic material increase using fillers. However, it also helps in decreasing the overall density of the plastic material, thereby reducing the weight and bulk of the final product. Lightweight and high strength are what injection molding is all about.
Furthermore, manufacturers use fillers in order to increase the heat resistance of products. Small plastic parts used in various industries like auto manufacturing or kitchen products need durability and flexibility.
This is because such products usually face high/low temperature and pressure. Manufacturers use Nylon (Polyamide) for quick-release buckles and passenger seats in public transport. For refrigerators, manufacturers use Acrylics as refrigerators store food at low temperatures, and for knife handles, they use polyoxymethylene (POM).
Whereas, the traditional method of molding plastic using lacks these characteristics and has its own limitations both in production and designing. The modern methods of injection molding are versatile and are also equipped with bulk production.
Cost-effectiveness and Less-Wastage in Injection Molding:
Plastic injection molding factory, considering the prevailing environmental degradation, is one of the sustainable manufacturing industries. As known, plastic is one of the non-biodegradable materials which is causing and destroying the ecological setup of the global world.
The conventional method of plastic molding involves the cutting of large plastic pieces into smaller ones leaving a large amount of plastic solid waste material.
In addition, injection molding is an automated process that involves a minimal amount of human labour. The invention of modern machinery to perform molding using computer-operated machines and robots has revolutionized the plastic world. This thus makes injection molding a cost-effective process.
Unlike the conventional method, which involves human labour, the injection method reduces the labour incentive. The injection molding units use software and technologies like CAD and CAM. The ability of the system to design precise and accurate design in one go.
This makes the product ideal, thereby reducing the chances of recreation. It also reduces the cost by 25 times as compared to the conventional method.
Final Words onPlastic Injection Molding Factory
It goes without saying that plastic injection molding is the most popular method of plastic production.
The foregoing points are some of the benefits that the modern system is offering. Therefore, this is the best method that offers durability, precision, creativity, and is cost-effective.
6 Benefits That Would Make You Want to Automate Your Plastic Molding Process Today!
Automation in Plastic molding is experiencing a rising trend. Automated plastic molding machines made up 32% of all the machines sold in 2019, which has risen from 18% in 2010. Many ambitious molders opt for automated plastic-molding machines for the efficiency that the robots confer upon this process.
What is Plastic Molding?
If you are here looking for benefits of automation in plastic molding, chances are you already know what plastic-molding is. But still, let us brush up your knowledge a bit, and then we'll get to the pros in a moment.
Plastic moulding is a process of converting molten plastics into well-defined shapes and sizes. The injection molding machine melts granular plastics first. And then, it injects the molten polymer into a mold of any shape and size.
After being injected into the mold, the machine applies pressure to the molten plastic and cools. This way, the plastic solidifies and takes the shape of the cavity inside the mold. The mold then opens up, drops the plastic piece, and closes for the next 'shot,' and completes one cycle of the process.
A typical production cycle can take anywhere from 2 seconds to up to 120 seconds to complete.
What is Automation in Plastic Molding?
Automation of a process translates into the integration of innovative technology and smart robotics into any process. An automated process offers increased productivity, capacity, and efficiency compared to a non-automated, fully manual process.
The world is getting more involved in developing ultra-modern technology. People want technology to aid humans in every field and reap smart and efficient robots' benefits. The injection molding industry keeps up with the fast-paced world and takes immense interest in the automation of their processes.
Automation of the plastic moulding process gives the molders an edge over their competitors who are yet to integrate automation with their process. Now, to efficiently compete with their 'automated' peers, more and more molders are handing their processes over to the robots.
How is Automation Enhancing the Plastic Molding Process?
Automation is effectively augmenting the plastic-molding process by decreasing cycle times and ensuring consistency in product quality. Here are just a few of the many advantages that justify why plastic moulding automation is imperative in today's world.
1. Increases Productivity
Employing robots to perform specific tasks in your injection molding process will lead to increased productivity. Unlike humans, robots never sleep. They never take breaks. Moreover, they don't need to go home after their shift is over. Hence, an automized plastic-molding process can stay in operation throughout the day, seven days a week.
Therefore, by automizing the molding process, you can keep manufacturing and selling products without frequent breaks and enjoy increased revenue.
2. Increases Production Capacity
With increased productivity comes increased production capacity. Automated machines are capable of producing plastic-molded parts at a much higher rate than manual machines can. The increase in production rate is because automated machines work faster, without a pause. Thus, they are often capable of producing thousands of perfectly molded plastic pieces in just one day!
3. Ensures Consistency in Product Quality and Specifications
Humans tend to make mistakes. It is normal. But a mistake is not just a mistake in the plastic moulding industry. It is a loss—a loss of time, effort, and of course, money. In manual molding processes, chances of the product specifications deviating from customer-defined parameters are high, which leads to losses in terms of lead time and raw material.
However, once programmed appropriately, machines can roll out plastic parts in every cycle that match exactly with the specifications fed to the machine—thus adding consistency to the molding process's throughput.
4. Automation Minimizes Cost
The common idea associated with plastic moulding automation is that it is bound to cost you an arm and a leg to get robots to do the tasks that human workers are already doing.
However, contrary to this belief, integrating automated machines in your process saves you a lot of money. How? Firstly, a single machine takes the place of multiple workers, which means you save on the cost that you may spend on these workers' salaries and other incentives.
Moreover, an automated plastic molding process produces fewer defective parts, which means you save money on the raw material. Furthermore, since automizing optimizes the entire process, this means robots will yield a significant return on investment very quickly.
5. Optimizes the Process.
Automating your plastic molding process is a sure-fire way to optimize the entire process. Automated plastic moulding machines produce high-quality parts in every cycle, yielding fewer plastic parts to discard. Consistent-quality production saves a lot of raw material that would've otherwise been wasted if the produced part was defected and rejected.
Moreover, automizing the plastic moulding process saves up a lot of labor as machines clean any leftover plastic that tends to solidify in the mold. They also load molded plastic parts on the conveyers. Thus, they eliminate the need for humans to do such primitive tasks and allow you to assign your human workforce tasks out of the machines' performance scope.
6. Lowers the Risk of Workplace Injuries
An industry such as the plastic molding industry that involves a lot of heat in the form of molten plastic and heated plastic parts runs a high risk of worker injury.
Moreover, the plastic molding process requires repetitive tasks such as removing molded-plastic parts and loading them on a conveyor. Then packing them and preparing them for shipping. All of these tasks are not only tedious but monotonous and excruciatingly exhaustive. Thus, they may lead to elevated-stress injuries among the workers.
Therefore, by employing automated machines to do all the highly repetitive tasks, you can save your workers from work-related injuries and utilize their capabilities in a more productive and less physically exhausting area, such as operating the machines or programming the robots.
Most people often criticize robots and automated machines for stealing human jobs. However, the reality lies at the opposite end of this spectrum. An automated plastic moulding process does not replace humans with robots, but they create better higher-paying jobs.
These robots control the potentially harmful aspects of the processes. And allow humans to control and monitor the process while staying far from their life-threatening aspects.
Moreover, they prevent exhaustion and stress injuries among workers by performing repetitive tasks that are the trademark of the plastic moulding industry efficiently without getting tired.
Thus, the automation of plastic moulding has innumerable virtues not only for the plastic molding owners but for the workers as well. Automated machines reduce human downtime, lead time, cycle time and increase profits, all the while ensuring proper health and safety of the workers
The gross profit margin of kechuang board companies exceeds 50%, and the pharmaceutical industry ranks first
China Net Finance Daily, May 29 (Reporter Guo Medicine, Intern, Zhu Zhengxue) The establishment of the Kechuang Board has brought more opportunities for a display to many prominent R&D kechuang board enterprises. According to the iFinD statistics of Flush Huan, as of May 28, 105 companies have been listed on the kechuang Board. The average gross profit margins of these companies in 2017-2019 were 51.77%, 52.63%, and 53.49%, respectively. The trend is that competitiveness continues to increase, and in 2019, more than 100 companies have positive returns on net assets.
Median gross margin exceeds 50%
Gross profit margin is one of the important indicators to measure product competitiveness and profitability. In 2019, the average gross profit margin of 105 listed companies of kechuang board companies was 53.49%, and the median gross profit margin reached 50.32%, which was also an increase from 2018. The gross profit margin of all companies exceeds 10%, and the interest rate of 39 companies is above 60%, accounting for 37.14%.
Among them, Baolan ranked first with a gross profit margin of 96.46%, and Microchip Biotech ranked second with a gross profit margin of 95.81%. In addition, the gross profit margins of 52 companies such as Amethyst Storage, Ruichuang Weina, and Platinum are between 30%-60%. It is worth noting that the 55 companies of Kechuang Board Company Bannan New Pharma, and Pumen Technology have improved their gross profit margin in 2019 compared with 2018, and 33 of them have increased their gross profit margins from 2017 to 2019.
According to Shenwan's first-level classification, since the establishment of the kechuang board, there are 105 listed companies, mainly concentrated in 19 sub-industries, such as non-metallic minerals, pharmaceuticals, and special equipment manufacturing, including pharmaceuticals. Compared with 2018, the average gross profit margin of 12 industries including the technology service industry and food manufacturing industry has increased in 2019.
Four of the top 10 companies in the gross profit margin of Kechuang Board are concentrated in the pharmaceutical manufacturing industry, software, and information technology services, and there are also special equipment manufacturing industries. The top 10 companies with a net return on equity are mainly concentrated in the pharmaceutical manufacturing industry, followed by the software and information technology services industry and the computer, communications, and other electronic equipment manufacturing industries.
Gross margins generally increase
In 2019, among the 19 sub-sectors of the Science and Technology Innovation Board, the pharmaceutical manufacturing industry ranked first in the industry with an average gross profit margin of 72.12%, and it has increased from 2018. Multiple policy support and planning.
Specifically, in addition to Zejing Pharmaceuticals not yet profitable, the average gross profit margin of 13 other companies in the pharmaceutical manufacturing industry can reach 77.66%, and the gross profit margins of 10 companies including Tebao Biological, Huaxi Biological, Haohai Shengke, and Borui Pharmaceutical All are concentrated in more than 70%, of which the core gross profit rate of Weixin is the highest, reaching 95.81%, which is the leading enterprise in the industry.
As shown, the average gross profit margin of the software and information technology services industry will be the second in the industry in 2019 and 2018, and 2019 will increase compared to 2018. In 2017, the "Software and Information Technology Services" Industry Development Plan (2016-2020) released by the Ministry of Industry and Information Technology provided guidance and financial support for the national software and information technology services industry, which is of great significance for promoting the development of the industry.
As of now, there are 19 listed companies in the technology board software and information technology service industries. The average gross profit margin of the industry in 2019 reached 66.04%. The gross profit margins of 11 companies such as Hongruan, Kingsoft Office, and Shanshiwangke all exceeded 60%. Among them, Baolan's gross profit margin was 96.46%.
In addition, the special equipment manufacturing industry has also achieved the average gross profit margin for two consecutive years and ranks in the forefront of the industry. Among the 22 companies listed in this industry, 12 gross profit margins are mainly concentrated in the range of 40%-70%, accounting for 54.55%. The gross profit margin of the other five companies was higher than 70%, accounting for 22.73%. Huafeng Measurement & Control, Xinmai Medical, Ruisong Technology, and other 11 companies have gross margins in 2019 exceeding 2018, and gross profit margins are in the improvement stage.
Guangdong is a major manufacturing province with a complete range of industries. However, in the process of industrial transformation and upgrading, "bottleneck" issues such as core technologies remain prominent. Recently, the Guangdong Provincial Department of Industry and Information Technology released the "Guangdong Province Development Plan for Cultivating High-end Equipment Manufacturing Industry" (2021-2025, draft for comments) recommending that it be transformed into manufacturing high-end CNC machine tools, aerospace equipment, satellites, and their applications. Railway transportation equipment, marine engineering equipment, and other important bases for manufacturing high-end equipment nationwide.
The solicitation draft proposes that by 2025, Guangdong will establish multiple national and provincial innovation centers and laboratories to promote breakthroughs in key technologies and key components in key areas. The annual income of the high-end equipment manufacturing industry will increase by more than 6%. Cultivate a group of industry leaders with international influence and independent brand value.
The consultation draft shows that Guangdong has now cultivated a number of equipment manufacturing enterprises and emerging enterprises, and its economic growth has been ranked first in the country for 30 years. But at the same time, the development of the high-end equipment manufacturing industry also faces many challenges: including the key core technology is constrained by people, independent research and development and innovation capabilities are insufficient, the problem of "jam neck" is still prominent; the foundation of heavy equipment is relatively weak, the industrial supporting system is not perfect, and high-end CNC systems, High-reliability electric spindles, cutting tools and other key components depend on the existing supporting equipment, and the large-scale overall machine enterprises are seriously insufficient in their relevance and supporting capacity to small and medium-sized enterprises.
The consultation draft pointed out that Guangdong's high-end equipment manufacturing industry is in a critical period of transforming from element-driven to innovation-driven to digital, networked, and intelligently upgraded. It will pass five key tasks and five key projects. Complete the development goal of maximizing high-end equipment manufacturing in 2021-2025.
Tang Yue, Deputy to the National People's Congress and Chairman of Chutian Technology: Promoting the R&D of Biopharmaceutical Equipment to Meet the "Era of Pharmaceutical Industry 4.0
⊙Reporter Xia Zihang ○ Editor Xu Rui
Just as the National People's Congress deputy, Chu Tian Technology Chairman Tang Yue foresaw a few years ago, where the pharmaceutical industry is fully entering the "pharmaceutical industry 4.0 era." In his view, it is very important to deepen the public health reform of the disease control system, establish a modern disease control management system, and accelerate the development of biopharmaceutical equipment.
Develop pharmaceutical equipment to help prevent and control COVID-19
"The new coronavirus, which has a high infection rate, a long incubation period, and multiple transmission routes, poses a huge challenge to the world's pharmaceutical industry." Tang Yue said.
At this year's two national conferences, Tang Yue put forward "suggestions on accelerating the development of biopharmaceutical equipment and improving local disease prevention and control capabilities." "Biopharmaceuticals are an important part of the national economy and have a closer relationship with people's livelihood. The main popular figure Tang Yue said that at present, the gap between the level of domestic biotechnology and biopharmaceutical core equipment is far from the world's advanced level.
In response to this problem, Tang Yue suggested that the state should introduce supporting policies to encourage the development of biopharmaceutical equipment, focusing on enhancing the emergency production capacity of epidemic prevention and control products; further promoting traditional Chinese medicine, accelerating the research level of Chinese medicine preparation equipment, and promoting Chinese medicine preparation equipment Quickly realize automation, digitalization, and intelligent upgrades; at the same time, encourage school-enterprise cooperation to achieve integrated development of production, education, and research, make full use of talents from universities, research institutes, R&D, technological advantages, and enterprise platforms and market advantages, and actively promote R&D and production, Close cooperation in sales.
The arrival of "the era of pharmaceutical industry 4.0"
A few years ago, Tang Yue said to the Shanghai Securities Journal reporter that in the future, the medical equipment industry will usher in a continuous huge dividend in the world, that is, "pharmaceutical industry 4.0" and the upgrading of pharmaceutical intelligent manufacturing. The direction of development will be obvious after 5 years, and there will be changes in the outline after 10 years. In Tang Yue's view, "Pharmaceutical Industry 4.0" can greatly reduce the hidden dangers of medical safety.
According to reports, pharmaceutical intelligent manufacturing and "Pharmaceutical Industry 4.0" can realize real-time, online, full-range, all-round automatic monitoring of pharmaceutical manufacturing and circulation consumption, and automatically generate data (and cannot be tampered with), automatically read data, Automatically store data to the cloud, zero delays, no dead ends, no blind spots. According to the authorization of the law, regulatory authorities, drug producers, and consumers can consult and retrieve relevant data.
Tang Yue believes that in the future, high-end pharmaceutical equipment, "pharmaceutical industry 4.0" and intelligent manufacturing will be regarded as "rigid demand" for pharmaceutical factories. Based on long-term foresight, Chutian Technology has successfully developed some intelligent pharmaceutical production robots and related production lines using automation and information technology and is transforming into an EPC service provider that builds a "pharmaceutical industry 4.0" smart factory overall solution.
The 2019 annual report shows that Chutian Technology's industrial layout has begun to show its advantages. The traditional advantage of Chutian Technology lies in the liquid pharmaceutical equipment, and its production and sales are at the forefront of the industry; Chutian Huatong, a wholly-owned subsidiary, is a professional research and development of pure steam generator, multi-effect distilled water machine, purified water preparation system, and other products. Manufactured pharmaceutical equipment manufacturing enterprise; Military Pharmaceutical Engineering Design Service of Sichuan Pharmaceutical Design Institute, a wholly-owned subsidiary; Chutian Robot, the holding subsidiary's main products are medical and medical robots; in 2019, Chutian Technology has added an intelligent Chinese medicine machinery product line.
Chutian Technology recently stated on the interactive platform that Sichuan Pharmaceutical Design Institute, a wholly-owned subsidiary of the company, has the design and construction capabilities of the P3 Biosafety Laboratory. During the epidemic prevention and control period, Sichuan Medical Design Institute undertook the design of the high-level biosecurity laboratory (P3) of the Eighth People's Hospital of Guangzhou City, which was highly recognized by hospital experts.
Currently, Chutian Technology is planning a follow-up merger and acquisition of ROMACO. ROMACO is currently the seventh-largest medical equipment company in the world and a senior solid preparation packaging manufacturer. Its products have entered more than 100 countries and regions in the world.
"At the time I was being consulted and my wife was dispensing medicine. When I am the busiest, I will call my cousin to take care of them. Many people in the village come here to see a doctor. "
Speaking of which, Dr. Li's hand in the clinic shook slightly. But the white coat and hair still maintain the rigor of the past, meticulous.
The plaque after the unified reconstruction of the streets has faded, and the outer walls are covered with medical notices and aftertastes of Chinese medicine and disinfection water. All the decorations are the same as the older Dr. Li and his wife: traditional, stubborn, and deadly.
This is a typical small self-employed clinic with a couple of "1 doctor + 1 pharmacist", which is what most medical "couple shops" look like.
"Now that the nurse has resigned, you must clean and disinfect yourself. You can get full every month." Dr. Li took off his glasses, drank strong tea, and took a long breath.
In the half-day of the interview, there was indeed only one guest in the pharmacy in front of us to buy Band-Aid. In addition, most of the time, Dr. Li and his wife Jiang Yaoji are studying how to use the latest online purchase software. As far as the two old doctors are concerned, the learning process is not simple. Finally, they still had to embarrassingly choose to call the service staff of the original pharmaceutical company.
However, once started, the sales staff will follow the software introduction and "enthusiastically" recommend Dr. Li to participate in the clinic upgrade project, and encourage: "Several clinics in your area have joined, and your traditional clinic is outdated. No, It doesn’t matter, we can come over to help you personally."
In response, Dr. Li refused without thinking. He hung up the phone, turned back to "the theory of relativity intelligence," and asked: "I don't understand. In the hospital, our old doctors are also somewhat famous, and the registration fee is a few yuan more expensive. Now that the Internet is coming, should we damn it? "
"Dare you dare to see a doctor on the Internet?"
Before opening his own clinic, Dr. Li was an orthodox medical student of that era and the successor dean of a township hospital.
“After I took office in 2005, the hospital was sold. I couldn’t do anything except seeing a doctor, so I rented a house and opened a clinic. I was in charge of injections, and my wife became a pharmacist. Whenever It is very busy at noon, often eating cold meals or not eating at all. There is no way, once the patient enters the door, we must receive him immediately."
But with this desperate hard work and excellent medical skills, this small clinic of only a few tens of square meters became famous locally in only one year. In 2010, Dr. Li simply bought a facade and expanded the clinic on "his own place".
"He looks fierce. In fact, he has always been an idealist. Those who do not need injections only need oral medicine. In the past SARS, this medicine was very expensive. If you give him more money, he still gets angry. There are six to seven clinics on this street, familiar (people) come often (Dr. Li's clinic), and people who often come from nearby cities..." Li's neighbor quietly asked "Intelligent Relativity".
However, when a company is doing too well, the capital that exudes "fishy smell" will always squeeze into this field and start to compete. In the eyes of capitalists, even life-saving medical treatment is nothing but "business."
Data from the China Health Statistics Yearbook show that between 2010 and 2017, the number of clinics in non-public grassroots medical and health institutions increased from 173,434 to 211,572, an increase of about 22%. The proportion of the total number of institutions rose from 41% to 54%.
Also at that time, Dr. Li and his wife felt that the (clinic) became more and more difficult to do.
Especially in June 2015, "Several Policies and Measures for Promoting the Rapid Development of Social Medical Treatment" (hereinafter referred to as "Measures") was issued. The state proposed to insist on opening medical treatment and implemented "non-prohibited entry" for social capital After the gradual progress, the feeling becomes more obvious.
The "solution" divides qualified social medical institutions into the scope of medical insurance fixed points and implements the same policies as public medical institutions. This solves the medical insurance problem, and also allows the Internet operation model to explode rapidly after the capital officially enters the market, making medical "self-employed" even more difficult to chase.
DNA, also known as deoxyribonucleic acid, we know that biological cells contain a large number of important biological macromolecules, basically one of them is a nucleic acid. DNA is a long polymer composed of repeating nucleotide units and is also a kind of nucleic acid. DNA carries the genetic information necessary for RNA and protein synthesis, and it is an indispensable macromolecule for biological development and normal operation. Before the cell divides, DNA replicates the genetic information of the organism during the replication process. Because it contains complete genetic information, people continue to study it.
At first, when people did not have the concept of DNA, the Swiss biochemist Friedrich Michelle had already separated this substance from the pus of the surgical bandage. But it was not called DNA at the time, but because this microscopic substance was located in the nucleus of the cell, it was called nuclear protein by everyone. It was more than 150 years ago. After this incident, people are just like opening the door to a new world, and a group of scientists is devoted to the study of genes.
After 90 years of exploration, Matthew Mercerson and Franklin Starr confirmed the replication mechanism possessed by DNA in the experiment and inspired the later Creek team to conclude that the genetic code is composed of three The bases are composed in a non-repetitive manner and are called codons. Later, some scientists solved the genetic code formed by these codons in 1961. Therefore, modern gene sequencing projects have also gradually begun.
Current research results divide DNA into three types: single-stranded DNA, closed-loop DNA, and junk DNA. Among them, single-stranded DNA has been studied more, and sequencing methods and technological methods are also more diversified. However, there has been little research on circular DNA, because the lack of effective methods for research and sequencing has hindered progress in this area.
It is understood that circular DNA is very common in the genomes of bacteria and viruses. Circular DNA refers to a closed circular DNA structure located outside the chromosome. Compared with free linear DNA, this circular DNA is not easily degraded by nucleases and is more structurally stable. Moreover, circular DNA is also widely present in various eukaryotes, including humans, with high tissue and disease specificity.
Recently, scientists have discovered a large amount of circular DNA in the nucleus of humans and plants, and also found this circular DNA in cancer cells that are not valued by people. After inferred by experts, it may even be able to reproduce rapidly with cancer cells. There is a certain correlation. Although the traditional view has always been that eukaryotic genomes usually form stable linear chromosomes, new research shows that whether in normal somatic cells or cancer cells, there is a large amount of extrachromosomal circular DNA, and even more, genetic information is stored.
Based on this, scientists have begun to investigate the role of circular DNA in cancer in recent years and overcome their sequencing technology difficulties. Kung Fu takes no pains. According to the physicist organization network, on May 14, a Canadian biologist invented a new tool called CIDER-Seq, which can sequence circular DNA. In fact, they designed a new algorithm based on the knowledge of molecular biology and bioinformatics and used this algorithm to obtain the complete sequence of circular DNA in the experiment. This technique has now been published by researchers on the Internet for other scientists to analyze circular DNA sequences.
This time, the new tool breaks through the original technical difficulties in circular DNA sequencing, or it will provide scientists with more abundant and accurate data for future research. Because the research also shows that many viruses infected with crops have circular DNA, this new technology can also bring benefits to agricultural development. Not only that, but the expanded field of circular DNA research is also expected to promote research on viruses, agriculture, and even cancer.
As we all know, now is the era of rapid development of biology. As a major hot spot in biology, DNA sequencing technology is still relentlessly updated to help scientists dig out more secrets from DNA sequences. As Craig Venter, a well-known expert in human genome research and the chief scientist of Celera Corporation of America said: The meaning of deciphering the genome code is just like in the era when electricity was just discovered, no one can imagine a personal computer, the Internet same. I believe that in the future, the development and progress of sequencing technology can improve people's quality of life to a higher level.
Top scientists have sequenced genes for 1.5 million organisms worldwide. Is this a library or a tombstone?
The fires in Australia, the locust plague in East Africa, and the new crown virus swept the world... After many hardships in 2020, looking back at the opening remarks of Wandering Earth, it seems like a god's prophecy.
"These events are interrelated and closely related to the reduction of the earth's biodiversity." On May 24th, in a video connection across the ocean, Harris Lee, a member of the World Association of Top Scientists (WLA), a recipient of the 2011 Wolf Prize for Agriculture, and professor of evolution and ecology at the University of California, Harris Li Wen tells us.
Professor Li Wen proposed a large scientific project that he named "Earth Biogenome Project" (EBP's Earth Biogenome Project).
This 10-year, costing 5 billion US dollars, sequence, classify and classify the genomes of all 1.5 million known eukaryotes on the planet, will draw a DNA map of all living things on the planet, which is equivalent to Built the Earth Biology Library.
This research may lead to changes in medical treatment methods, solve the problem of global hunger, and create a new "Silicon Valley of Agricultural Science and Biotechnology" in the human backyard. Because of its groundbreaking and importance, EBP is known as the "Moon Landing Plan" of the biological world, and Professor Li Wen has also been rated as a "The Whole World Cataloger" by foreign media.
On May 22, on the 21st International Biodiversity Day, the United Nations announced this year's theme as "Nature, Life for All" (in the natural world). During this period, Professor Li Wen accepted our exclusive interview about the conservation and protection of biodiversity. The future of humanity and the current status of EBP projects and their long-term significance to biodiversity. At the same time, he also shared the current challenges of biology to the popularization of new crowns, and how the EBP project can help new crown pneumonia.
In April 2018, Professor Li Wen was in the Life Science Building at the University of California, Davis. He stood beside the 1998 sculpture by Clarksburg artist Roger Berry, which depicts a DNA sequence.
The unprecedented speed of global species extinction
Biodiversity (English: Biodiversity or Biological Diversity) is a broad concept that describes the degree of diversity in nature.
Although different scholars have different interpretations of biodiversity, it is undeniable that biodiversity resources are an important foundation for us to build civilization. Biological diversity is closely related to the food, therapeutic drugs, and quality of life on which we depend.
According to information published by the United Nations, the needs of at least 40% of the world’s economy and 80% of the world’s poor people come from biological resources. Most of the food, medicines, and raw materials needed for daily production and life are obtained from living things.
Biodiversity maintains ecological balance and maintains environmental stability; biodiversity is also an important object and driving force for human scientific research. In addition, the richer the diversity of life, the greater the chance of discovering new challenges such as drugs, economic development, and adaptation to climate change.
However, today's biodiversity is facing greater trouble than at any time in human history.
In 2019, the United Nations Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) released the "Global Natural State Assessment" report. The report points out that of the 8 million species in the world, 1 million are threatened with extreme extinction due to human activities. The average rate of global extinction is tens to hundreds of times higher than in the past 10 million years.
UN Secretary-General Antonio Guterres said that as we humans invade nature and consume important habitats for animals and plants, more and more species are being put at risk. This also includes our humanity and the future we hope for.
Since the outbreak of new pneumonia worldwide, meltblown fabrics have multiplied and become the core material of medical protective masks. In order to ensure that the Boomingshing medical production line of Changhong Technology's subsidiary needs to produce 3 million pieces of mask raw materials every day, and save procurement costs, and make full use of Changhong's powerful mold technology background technology, the group chairman Li Huanchang decided to establish on April 15, 2020. A technical team supporting the research and development of melt-blown fabrics to overcome the precision spinneret technology of melt-blown fabric molds and the production technology of high-temperature injection molding spray glue. The goal is to produce and sell core raw materials.
The first stage, to overcome the core technology of precision spinneret
This task of research and development and production of precision molds has been transferred to its subsidiary Shanghai Changmei Precision Moulds Ltd. On April 15, after receiving the task, Xu Yanping, the general manager of the company, personally selected the technical backbone to form a research and development team. It took only 3 days on April 18 to overcome the precise processing technology of the melter nozzle spinneret and complete the smooth assembly of the 600-hole nozzle module with high efficiency and high quality. Subsequent assembly of various specifications and models, such as 600-type aperture (0.15mm, 0.20mm, 0.25mm, 0.30mm), 1600-type aperture (0.20mm, 0.25mm, 0.30mm).
The second stage, to overcome the high-temperature injection molding production technology
In the coronavirus disease, time is life. On May 2, 2020, the melt-blown fabric production workshop began construction day and night at Changhong Technology's Shenzhen Pingshan Plant, and the equipment installation was completed con May 7 in only 6 days. Xu Yanping, general manager of the company, personally stationed on the front line of the workshop and worked hard with the process engineer to debug the day and night process. On May 8th, he overcame the production technology of high-temperature injection molding of melt-blown cloth. The best combination, 6 production lines to achieve smooth production. Meltblown cloth PFE99 (32L/min, 15pa/cm2), specifications (150, 175, 260), weight (0.22, 0.25, 0.30, 0.40), after testing and certification to achieve industry-leading excellent quality, daily capacity can be reached after capacity release 10 tons +, fully meet the self-production and sales demand of disposable medical masks, N95 mask raw material supply chain.
Changhong Technology is ingenious in fighting against epidemic disease, and we are all committed to the city. We have been working hard to provide high-quality products and services and work tirelessly for the cause of human health!
Shenzhen Changhong Technology Co., Ltd.
May 30, 2020